Recently the Department of Biotechnology-National Brain Research Center (DBT-NBRC) has developed Swadesh project for the management of neurological disorders.
NBRC is the only institute in India dedicated to neuroscience research and education.
About Swadesh Project:
Swadesh is the first large-scale multimodal neuroimaging database specially designed for the Indian population under one platform with big data architecture and analytics for different disease categories (picture given).
The plan has a big data architecture that proposes 6 modules for management and analysis. These modules include neurodegenerative [AD, mild cognitive impairment (MCI), Parkinson’s disease (PD)], neuropsychiatric (schizophrenia and bipolar disorder), neurodevelopmental (autism and epilepsy), diseases and other disorders related to COVID-19.
Equipped with indigenous Java based workflow environment and Python. Which provides it with quality control, data analysis reports and data backup.
Python and Java are both computer programming languages.
Importance:
It will be useful in multiple brain studies to understand Alzheimer’s disease and many neurological disorders.
Its development will facilitate the integration of multi-site data and collaborative research across the globe.
Neurological disorder
Neurological Disorders are diseases related to the Central and Peripheral Nervous System.
In other words, disorders involving the brain, spinal cord, cranial nerves, peripheral nerves, nerve joints, autonomic nervous system, neuromuscular junctions and muscles.
Type:
Non-communicable neurological disorders: including stroke, headache, epilepsy, cerebral palsy, Alzheimer’s disease and other dementias, cancer of the brain and central nervous system, Parkinson’s disease, multiple sclerosis ), Motor Neuron Diseases and other neurological disorders.
Neurological disorders account for 10% of the total diseases in India.
The burden of non-communicable neurological disorders is increasing in the country, mainly due to the aging of the population.
Contribution of Non-Communicable Neurological Disorders to Total Disability Adjusted Life-Years- DALY in India doubled from 4% in 1990 to 8 2% in 2019 and that of neurological disorders related to injury Contribution increased from 0·2% to 0·6%.
Known risk factors for neurological disorders include obesity, high blood pressure, air pollution, dietary exposure, excessive fasting, plasma glucose and high body-mass index.
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